the dude is Dominos Japan prez.
Hatsune Miku is, as he says, vocaloid. She's kinda old skool now but she's was the breakout singing-voice synth program that got the scene going. The scene is mostly Japanese, based around Nico Nico Douga, a members only site where people make stuff--music, art, videos--which they post to share. Once shared, they get coopted and themes and image trends start. One big thing is making music, having a vocaloid sing, then adding video, sometimes computer generated, sometimes real people. (From which scene did Danceroid emerge, I luvs them.)
The existence of this large social media sharing community has marketers loosing their shit. Miku is everywhere in Japan and almost nowhere in English-speaking countries. This ad, and a bunch of dumb spots for Toyota, are attempts to cashing in, but they HAVE NO IDEA!
When Japanese co-opt western culture, you get stuff like
Crazy Night. When Dominos co-opt Japanese you get freakish white men touching Mikus.