Yeah, I'm not sure it would go over that well. My students (who are a bit younger than college students, but not by much, my seniors are 17-19) like shows about pretty young people, unfortunately. I don't think they'd really get what is going on in Golden Girls or why certain characters are supposed to be funny.
In my classes Friends is a huge favorite, as is Gossip Girl (which is much too dirty and innuendo-filled to use in class, but they watch it on their own). Our Chinese English teacher shows them episodes of Felicity which is about college life and they really like that. Overall they prefer shows that they can relate to on some level or that show a sort of alternate reality version of their own lives.
I've also shown reality TV occasionally, like The Amazing Race. It is fast paced and doesn't require a huge English vocabulary to understand (they can watch it without subtitles and still get it), it has the contest element that makes it exciting, and the world travel gives them some interesting cultural lessons. I've thought of showing them Survivor too because I think they'd get a kick out of people eating rats and sleeping in shacks getting rained on and stuff trying to win a million.